Table 1. Univariate and multivariate analysis of factors affecting the OS of patients with OSCC.
| Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| IL-12RB1 expression in malignant cells (low vs. high) | 1.07 (0.57–2.01) | 0.842 | 1.10 (0.58–2.07) | 0.781 | |
| IL-12RB1 expression in non-malignant cells (low vs. high) | 0.50 (0.26–0.93) | 0.029* | 0.45 (0.24–0.86) | 0.015* | |
| Age (≤60 vs. >60) | 1.61 (0.84–3.07) | 0.150 | – | – | |
| Gender (male vs. female) | 1.12 (0.56–2.20) | 0.754 | – | – | |
| T classification (T1+2 vs. T3+4) | 1.16 (0.53–2.53) | 0.714 | 1.342 (0.60–3.00) | 0.473 | |
| LN metastasis (LN− vs. LN+) | 2.13 (1.11–4.10) | 0.023* | 2.34 (1.20–4.56) | 0.013* | |
| Histological (well vs. moderate) | 0.71 (0.26–1.95) | 0.503 | 0.74 (0.27-2.05) | 0.563 | |
| Histological (well vs. poor) | 0.74 (0.37–1.46) | 0.381 | 0.70 (0.34–1.34) | 0.255 | |
*P<0.05. OS, overall survival; OSCC, oral squamous cell carcinoma; HR, hazard ratio; CI, confidence interval; IL-12RB1, interleukin 12 receptor subunit beta 1; LN, lymph node.