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. 2022 Feb;10(3):133. doi: 10.21037/atm-22-118

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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There are significant differences in plasma metabolomics between the patient group and the control group. (A) The ellipse area of the PCA in the patient group and the control group represents the 95% confidence interval. (B) PLS-DA diagram of the patient group and the control group. (C) OPLS-DA diagram of the patient group and the control group. (D) Permutation diagram of the patient group and the control group. (E) Loading diagram of the patient group and the control group. (F) Splot plot of the patient group and the control group. PCA, principal component analysis; PLS-DA, partial least squares-discriminant analysis; OPLS-DA, orthogonal partial least squares-discriminant analysis; PC, principal component; P, patient group samples; C, control group samples.