Table 1. Instrument information.

Instrument	Model and specification	Manufacturer
Ultrasonic cleaning machine	F-060SD	Shenzhen Fuyang Technology Group Co., Ltd.
Vortex oscillator	TYXH-I	Shanghai Hannuo Instrument Co., Ltd.
High-speed refrigerated centrifuge	TGL-16MS	Shanghai Luxianyi Centrifuge Instrument Co., Ltd.
Freeze concentration centrifugal dryer	LNG-T98	Taicang Huamei Biochemical Instrument Factory
High-resolution mass spectrometer	QE plus	Thermo Fisher Scientific
High-performance LC	Dionex U3000 UHPLC	Thermo Fisher Scientific
Chromatographic column	ACQUITY UPLC HSS T3	Waters

LC, liquid chromatography.