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editorial
. 2022 Feb 7;28(5):502–516. doi: 10.3748/wjg.v28.i5.502

Table 1.

Risk factors for the development of colorectal cancer in patients with inflammatory bowel disease and recommended surveillance


High risk
Intermediate risk
Low risk
Risk factors (1) PSC; (2) Extensive involvement; (3) Moderate-severe active inflammation sustained over time (endoscopic or histological); (4) First-degree relative with CRC before age 50; (5) Stenosis or dysplasia detected during the previous five years; (6) Appearance of IBD at a young age; (7) If ileo-anal pouch: (a) Dysplasia; (b) Previous CRC; (c) PSC; and (d) Type C mucosa in the pouch (1) Extensive colitis with mild or moderate sustained inflammatory activity (endoscopic or histological); (2) Inflammatory polyps; and (3) First-degree relative with CRC after age 50 (1) Factors other than high and intermediate risk; and (2) If ileo-anal pouch: Without risk factors
Surveillance Annual Every three years Every five years

CRC: Colorectal cancer; IBD: Inflammatory bowel disease; PSC: Primary sclerosing cholangitis.