| A/B |
Statement: There are clear indications that growing up on a farm protects against the development of asthma and allergic diseases. |
| This is mediated by early unspecific immune stimulation, among others through the microbial composition of the house dust. |
|
Statement: A recommendation regarding the prevention of atopic diseases through child daycare cannot be given due to the heterogeneous study data. |
|
Statement: There is no proof that vaccinations increase the risk of allergies, but there are indications that vaccinations can lower the risk of allergies. |
|
Recommendation: All children, including children at risk, should be vaccinated according to the current recommendations. (A) |
|
Recommendation: When giving advice on the mode of delivery, it should be taken into account that children who were born through an elective caesarean section have a slightly increased risk of asthma. (B) |
| Level of evidence |
Kirjavainen 2019 (2++); Nicklaus 2019 (2++); Louis 2014 (2++); Brick (2+); Cheng 2014 (2+); Linehan 2014 (2+); Thestesen 2018 (1+); Baxter 2018 (1+); Rusconi 2017 (2+); Kahr 2015 (2+); Wu 2016 (2+); Sevelstedt 2016 (2++); Chu 2017 (2+); Lee 2014 (2+); Brandao 2016 (2+) |
| Level of consensus: |
Strong consensus |
