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. 2022 Feb 23;13:826007. doi: 10.3389/fpls.2022.826007

TABLE 1.

A list of the core coat protein complexes in plant post-Golgi trafficking.

Coat protein complex H. sapiens S. cerevisiae A. thaliana Accessory Proteins Known Cargo Motif Pathway
AP1 γ1, 2 γ1 γ1, 2 EPSIN, ? TGN/EE to PM
β1, 2 β1, 2 β1, 2 GGAs ?
μ1A, B μ1 μ1, 2 YXXØ*
σ1A, B, C σ1 σ1, 2 [D/E]XXXL[L/I]

AP2 αA, C α α1, 2 CALM, ? PM to TGN/EE
β1, 2 β1, 2 β1, 2 epsin, ?
μ2 μ2 μ2 ARH, YXXØ*
σ2 σ2 σ2 β-arrestin [D/E]XXXL[L/I]

AP3 δ δ δ ? ? EE to vacuole/lysosome, TGN/EE to vacuole/lysosome
β3A, B β3 β3 ?
μ3A, B μ3 μ3 YXXØ*
σ3A, B σ3 σ3 [D/E]XXXL[L/I]

AP4 ε ε ε Tepsin, ? TGN to vacuole, TGN to specialized compartments
β4 β4 β4 MTV ?
μ4 μ4 μ4 YXXØ*
σ4 σ4 σ4 [D/E]XXXL[L/I]

AP5 ζ ζ ζ SPG11/15 ? late endosome to TGN, ?
β5 β5 β5
μ5 μ5 μ5
σ5 σ5 /

TPC / / TSPOON (LOLITA) CALM, ? PM to TGN/EE
/ / TSAUCER (TASH3) Epsin,
/ / TCUP (TML) ARH,
/ / TPLATE β-arrestin
/ / TTRAY1,TTRAY2 (TWD40-1, TWD40-2)
/ / AtEH1(Pan1), AtEH12(Pan1)

Retromer VPS26 Vps26p VPS26A, VPS26B SNX3, ØX[L/M/V]; [ILMV]x[FY]xx2-13ØxØ or [FYW]x[FY]x3-15ØxØ; [-][-]x[-][ST]xØ Vacuole/lysosome to Endosome, Endosome to Golgi/PM
VPS29 Vps29p VPS29 SNX27,
VPS35 Vps26p VPS35B, VPS35C WASH

Retriever VPS26c / VPS26C SNX17, NPxY/NxxY
VPS29 / VPS29 CCC complex,
VPS35L / VPS35A WASH

SNX-BAR SNX1 Vps5p SNX1 SNX5/6, [ILMV]x[FY]xx2-13ØxØ or [FYW]x[FY]x3-15ØxØ; [-][-]x[-][ST]xØ
SNX2 SNX2A,SNX2B WASH

*Ø represent hydrophobic amino acid, and X represent any amino acid.