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Survival analysis of TRPA1 in 18 kinds of cancer using TCGA data
For the first time, the authors revealed that a tRF mimic (antisense derived from Chinese yew) interacts with AGO2 to directly target TRPA1 via the RNAi pathway, resulting in suppressing OVCA growth. This uncovered a new role of plant-derived tRFs and broadened our knowledge of therapeutics from plants.
