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. 2021 Oct 4;35(12):917–950. doi: 10.1089/ars.2020.8234

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© László Potor et al., 2021; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License [CC-BY-NC] (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

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FIG. 3. — Oxidation hotspots of globin in human complicated lesion. Trypsin-digested human complicated lesion (N = 5) was utilized for LC-MS/MS analysis. The image presents the location of Cys oxidation in the Hb chains. Hb was visualized with CAVER Analyst 2.0 software using PDB entry 1BUW. Hb, hemoglobin; LC-MS/MS, liquid chromatography with tandem mass spectrometry. Color images are available online.