Table 1.
Data of Patients with Carotid Endarterectomy and Healthy Volunteers
| Data of patients with carotid endarterectomy | |
| Sampling period (year) | From 2012 to January 2021 |
| Total sample number | A total of 78 were used for histology, 57 were used for spectrophotometric analysis, proteomic analysis, biochemical examination, molecular biology studies, RNA-sequencing |
| Gender | 47 Females (35%), 88 males (65%) |
| Age | 44–85 Years (average: 67.8 years, SD: 9.6 years) |
| Comorbidities and conditions that occurred in more than three patients | Hypertension (94%); peripheral artery disease (81%); ischemic heart disease (77%); obesity (62%); brain lacunar infarction (42%); type 2 diabetes mellitus (NIDDM; 38%), stroke (ischemic and hemorrhagic; 35%); hyperlipidemia (27%); coronary stent implantation (27%); myocardial infarction (23%); COPD (23%); hypothyroidism (19%), heart surgery—CABG (18%); bronchial asthma (15%); aortoiliac bypass surgery (12%); severe CKD (GFR <30; 12%); heart surgery—artificial aortic valve implantation (included TAVI; 8%); pacemaker implantation (8%) |
| Most frequent medications | Acetylsalicilic acid (91%); antacids (81%); beta-blocker (51%); diuretics (49%); allopurinol (42%); clopidogrel (42%); calcium channel blocker (40%); ACE inhibitor or ATII receptor antagonists (39%); statins (37%); alpha 1-receptor blocker (27); oral antidiabetic drugs (except insulin; 26%); warfarin or acenocoumarol (19%); citalopram (10%); carbamazepine (10%); piracetam (10%); insulin and insulin analogues (9%); folic acid (9%); levothyroxine (9%); alprazolam (9%); ipratropium-bromid (6%) |
| Data of healthy blood donor volunteers | |
| Sampling period (year) | From 2012 to January 2021 |
| Total volunteer number | 7 |
| Total sample number | 26 |
| Gender | 7 Males (100%) |
| Age | 25–62 Years (average: 42.5 years, SD: 13 years) |
CABG, coronary artery bypass graft; CKD, chronic kidney disease; COPD, chronic obstructive airway disease; GFR, glomerular filtration rate; NIDDM, non-insulin-dependent diabetes mellitus; SD, standard deviation; TAVI, transcatheter aortic valve implantation.