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. 2021 Sep 14;43(2):329–365. doi: 10.1210/endrev/bnab030

Figure 5.

Figure 5.

Pathophysiology of IBM. Cartoon representation of muscle fascicle cross-sections from healthy subjects and from IBM patients before and after treatment with corticosteroids. Different structural components of mature muscle fascicles are labeled to the left of each panel. Dotted lines aid in representing the change in fascicle size with disease progression.