Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Gene mutations leading to an activation of Wnt signaling (cluster 3) and derived molecular targets for a personalized therapy. Mutations in MAML3 and CSDE1 activate Wnt/ß-catenin signaling. Highlighted in red are potential drugs that address the molecular changes in cluster 3 PPGLs and are in preclinical evaluation.
