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. 2021 Jun 19;43(2):199–239. doi: 10.1210/endrev/bnab019

Table 1.

Penetrance of cluster 1–related PPGLs

Penetrance SDHB SDHA SDHC SDHD VHL
50 years 21%
60 years 42% and 22%, respectively 43%
80 years 25-65%
Lifetime estimate 22% 1.7% 8.3% 15-20%