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Most sensitive functional imaging modalities for cluster 1A/1B
| Functional imaging | SDHx-related (cluster 1A) | VHL-related (cluster 1B) | EPAS1(HIF2A)/PHD1/2/FH-related (cluster 1B) |
|---|---|---|---|
| First choice | [68Ga]-DOTA-SSA PET/CT | [18F]FDOPA PET/CT | [18F]FDOPA PET/CT |
| Second choice | [18F] FDG PET/CT ([18F]DOPA PET/CT for head and neck PGLs) | [68Ga]-DOTA-SSA PET/CT | [18F]FDG PET/CT |
