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Penetrance/prevalence, metastatic risk, location of cluster 2–related PCCs
| RET | NF1 | TMEM127 | MAX | |
|---|---|---|---|---|
| Penetrance | Around 50% (50%-80% multiple) | Around 7%-8% (12% multiple) | Penetrance unknown, prevalence around 2% (single tumors) | Penetrance unknown, prevalence around 1% (67% multiple) |
| Metastatic risk | <5% (3.5%) | Around 2%-12% | Mostly benign | Around 10% |
| Location | adrenal |
