Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Follow-up of asymptomatic cluster 2-mutation carriers
| Follow-up of asymptomatic mutation carriers | RET | NF1 |
|---|---|---|
| Clinical and biochemical evaluation | Initial screening by the age of 11-16 years depending on the specific mutation, then every 12 months (higher penetrance) Risk of primary hyperparathyroidism and medullary thyroid carcinoma (every 12 months calcitonin, calcium, PTH if applicable) |
Initial screening by the age of 10-14 years, then every 36 months (lower penetrance) |
