Table 1.
Patient characteristics by HER2 mutation status in the TCGA pan-cancer cohort.
| Characteristic* | Wild-type (%) | Mutation (%) | P value |
|---|---|---|---|
| Age (years) | |||
| <65 | 4713 (97.2) | 138 (2.8) | 0.095 |
| ≥65 | 3347 (96.5) | 121 (3.5) | |
| Sex | |||
| Female | 4206 (96.6) | 149 (3.4) | 0.106 |
| Male | 3782 (97.2) | 109 (2.8) | |
| Stage | |||
| I/II | 3913 (96.5) | 143 (3.5) | 0.997 |
| III/IV | 2735 (96.5) | 100 (3.5) | |
| Histological type | |||
| Non-SCC | 6324 (96.8) | 206 (3.2) | 0.007 |
| SCC | 1311 (98.2) | 24 (1.8) | |
| Histological grade | |||
| I/II | 1338 (96.8) | 44 (3.2) | 0.006 |
| III/IV | 1879 (94.9) | 102 (5.1) | |
*Based on available data.
SCC, squamous cell carcinoma; TCGA, The Cancer Genome Atlas.