Table 2.

Therapy response by HER2 mutation status in the pooled immunotherapy cohort.

Therapy and response*	Wild-type (%)	Mutation (%)	P value
Anti-CTLA-4
Non-response	102 (77.9)	7 (70.0)	0.567
Response	29 (22.1)	3 (30.0)
Anti-PD-1/-PD-L1
Non-response	111 (71.6)	3 (37.5)	0.040
Response	44 (28.4)	5 (62.5)
All
Non-response	220 (74.3)	10 (55.6)	0.081
Response	76 (25.7)	8 (44.4)

^* Response data were available in 314 patients.