Table 3.
Therapy and DC* | Wild-type (%) | Mutation (%) | P value |
---|---|---|---|
Anti-CTLA-4 | |||
PD | 79 (60.3) | 5 (50.0) | 0.522 |
DC | 52 (39.7) | 5 (50.0) | |
Anti-PD-1/-PD-L1 | |||
PD | 60 (38.7) | 1 (12.5) | 0.135 |
DC | 95 (61.3) | 7 (87.5) | |
All | |||
PD | 144 (48.6) | 6 (33.3) | 0.207 |
DC | 152 (51.4) | 12 (66.7) |
* Response data were available in 314 patients.
DC, disease control (defined as response or stable disease); PD, progressed disease.