Table 3.

Follow-up parameters associated with DLCO alteration at 3 and 12 months

	3 months			12 months
	Normal DLCO N = 49	Altered DLCO N = 36	p-value	Normal DLCO N = 65	Altered DLCO N = 8	p-value
6MWT
Number evaluated	46 (93.9%)	33 (91.7%)	0.6948	59 (90.8%)	7 (87.5%)	0.5727
Walked distance (m)	510 (450–570)	443 (370–525)	0.0199	540 (500–612)	545 (420–590)	0.4620
Walked distance < theoretical distance (%)	23 (50.0%)	27 (81.8%)	0.0038	15 (25.4%)	3 (42.9%)	0.3800
Hospital Anxiety and Depression Scale
Anxiety ≥ 11	6 (12.2%)	1 (2.8%)	0.2302	7 (10.8%)	0 (0.0%)	1
Depression ≥ 11	2 (4.1%)	1 (2.8%)	1	3 (4.6%)	0 (0.0%)	1
MOS-SF36
Physical functioning	80 (60–90)	65 (27.5–85)	0.0651	75 (65–90)	72.5 (60–82.5)	0.4695
Role-physical	50 (0–100)	25 (0–87.5)	0.3489	100 (25–100)	75 (0–100)	0.3428
Bodily pain	62 (42–84)	72 (50.5–84)	0.6144	62 (41–84)	63 (57–87)	0.5058
Mental health	80 (60–92)	76 (64–90)	0.6822	76 (60–88)	86 (74–90)	0.3928
Role-emotional	66.7 (0–100)	100 (0–100)	0.3206	100 (33.3–100)	83.3 (33.3–100)	0.9074
Social functioning	75 (50–100)	68.8 (43.8–100)	0.5403	75 (50–100)	87.5 (81.3–100)	0.2072
Vitality	55 (45–70)	55 (47.5–72)	1	60 (45–75)	57.5 (52.5–72.5)	0.8253
General health	67 (57.82)	63.5 (54.5–72)	0.3808	67 (52–82)	58.5 (52–67)	0.5428
CT scan
Missing data	5	0		9	0
Abnormal scan	41 (93.2%)	36 (100%)	0.2481	56 (88.9%)	8 (100%)	1
Reticulations	37 (90.2%)	32 (88.9%)	0.8458	52 (92.9%)	6 (75.0%)	0.5928
Traction bronchiectasis	22 (53.7%)	31 (86.1%)	0.0029	38 (73.1%)	6 (75.0%)	1
Honeycombing	2 (4.9%)	4 (11.1%)	0.4099	3 (5.8%)	0 (0.0%)	1
Ground-glass opacity	29 (70.7%)	27 (75.0%)	0.6748	30 (57.7%)	2 (25.0%)	0.1300
Emphysema	4 (9.8%)	10 (27.8%)	0.0408	6 (11.5%)	6 (75.0%)	0.0004

Values are presented as medians (interquartile ranges) or number of patients (percentages)

6MWT  six-minute-walk test, MOS-SF36  medical outcomes study short form 36-item questionnaire, CT scan  computerized tomography scan