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. 2022 Mar 9;2022(3):CD015125. doi: 10.1002/14651858.CD015125

Comparison 1. Inhaled corticosteroids (plus standard care) versus standard care (with or without placebo).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 All‐cause mortality at up to day 30 3 2132 Risk Ratio (M‐H, Random, 95% CI) 0.61 [0.22, 1.67]
1.2 Admission to hospital or death at up to 30 days 2 2025 Risk Ratio (M‐H, Random, 95% CI) 0.72 [0.51, 0.99]
1.3 Symptom resolution: all initial symptoms resolved (asymptomatic) at day 14 2 1986 Risk Ratio (M‐H, Random, 95% CI) 1.19 [1.09, 1.30]
1.4 Symptom resolution: mean time to recovery (days) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
1.5 Symptom resolution: all initial symptoms resolved at up to day 30 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
1.6 Quality of life at day 28: mean in well‐being (WHO‐5 Well‐Being Questionnaire) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
1.7 Serious adverse events 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
1.8 Adverse events 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
1.9 Infections 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected