| Clemency 2021 |
Low risk of bias |
We judged this domain low as the randomisation process was adequate because it is done remotely and moreover consider concealment adequate. Slight baseline differences were most likely due to chance. |
Low risk of bias |
Deviations were balanced and most likely not due to the trial context in this double‐blinded trial. |
Low risk of bias |
Although there were around 5% of participants lost to follow‐up, it seems not probable that the outcome has been affected relevantly by those dropouts. |
Low risk of bias |
We judged low risk of bias, as the combination of structured contacts and eDiary provided a high probability that the outcome would be detected. |
High risk of bias |
We judged this domain high due to a subsequent addition of this outcome to the trial protocol month after having completed the trial. |
High risk of bias |
Overall, we judged high risk of bias due to subsequent addition of this outcome (probably during the analysis process). |
