| Clemency 2021 |
Low risk of bias |
We judged this domain low as the randomisation process was adequate because it is done remotely and moreover consider concealment adequate. Slight baseline differences were most likely due to chance. |
Low risk of bias |
Deviations were balanced and most likely not due to the trial context in this double‐blinded trial. |
Low risk of bias |
Some adverse events lead to trial discontinuation. But they had been reported, so we do not assume, that the ~5% "lost to follow up" affected the outcome. |
Low risk of bias |
We judged low risk of bias, as the combination of structured contacts and eDiary provided a high probability that the outcome would have been detected. |
Low risk of bias |
We judged this domain low due to pre‐specification of the outcome. |
Low risk of bias |
Overall, we judged low risk of bias. |
