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. 2022 Feb 23;12:740603. doi: 10.3389/fneur.2021.740603

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Copyright © 2022 Mistral, Roca, Maggia, Tucholka, Forbes, Doyle, Krainik, Galanaud, Schmitt, Kremer, Kastler, Troprès, Barbier, Payen and Dojat.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation procedure. Left: five realistic TBI lesion cases were constructed with low (green) and high (red) artificial MD values. The ground truth was predefined for automated and manual lesion delineation comparison. Right: Twelve TBI patients were included, each with three types of MR image. Manual and automated delineation results were quantitatively compared for 10 patients. The ground truth was defined as the consensus of expert annotations (“consensual inter-raters ground truth”), calculated using STAPLE (10).