TABLE 2.

EV production inhibitors that targeting PADs.

No.	Name	Structure	Target		Activity	References
				E. coli VCS257	S. aureus subsp. sureus Rosenbach
13	GSK199		PADs	Reduce 66.4% EV production at 10 μM	Reduce 22.5% EV production at 10 μM
14	BB-Cl-amidine		PADs	Reduce 53.8% EV production at 5 μM	Reduce 7.6% EV production at 5 μM
						Kosgodage et al., 2019b
15	Cl-amidine		PADs	Reduce 42.4% EV production at 50 μM	Reduce 12.5% EV production at 50 μM
16	AMF30a		PADs	Reduce 28.2% EV production at 5 μM	Reduce 3.4% EV production at 5 μM