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. Author manuscript; available in PMC: 2022 Mar 9.
Published in final edited form as: Vaccine. 2020 Feb 3;38(10):2307–2314. doi: 10.1016/j.vaccine.2020.01.068

Figure 1: Mean Post-treatment Percentage Shift in Body Weights from Baseline over Time, by Group.

Figure 1:

Guinea pigs (n = 8 per group) were treated with 10, 15, or 20 mg/kg of ciprofloxacin administered via IP injection TID for 14 days. The body weights were recorded daily. Based on the analysis of the weight loss, the 10 mg/kg dose of ciprofloxacin was well tolerated by guinea pigs, while tolerability was low and moderate at the 20 and 15 mg/kg. The decrease in body weight, compared to baseline, in the group administered 20 mg/kg of ciprofloxacin was significantly greater than in groups receiving lower dose levels of the antimicrobial (P < 0.05).