Table 3.

Multivariable HRs for NRM and OS

	NRM			OS
	HR (95% CI)	P		HR (95% CI)	P
SCI score
0			Reference
1	2.04 (1.11-3.74)	.021		1.71 (1.13-2.59)	.0105
2	3.09 (1.66-5.73)	.000		2.6 (1.7-3.97)	<.001
3	5.03 (2.64-9.6)	.000		3.15 (1.95-5.07)	<.001
≥ 4	7.04 (3.61-13.73)	.000		4.08 (2.46-6.77)	0
Regimen
Melphalan-based			Reference
TBI-based	0.89 (0.53-1.5)	.670		1.03 (0.71-1.49)	.888
Karnofsky performance status
≤ 80			Reference
90 − 100	1.53 (1.08-2.17)	.017		1.53 (1.17-2)	.002
CIBMTR disease risk
Low/Intermediate			Reference
High	1.05 (0.7-1.58)	.818		1.31 (0.97-1.76)	.078
Unclassifiable	0.57 (0.27-1.18)	.130		0.53 (0.28-0.98)	.042
Recipient CMV serostatus
Negative			Reference
Positive	1.13 (0.8-1.61)	.491		1.19 (0.91-1.57)	.197
Donor type
Matched related			Reference
Matched unrelated	1.1 (0.73-1.65)	.662		0.92 (0.68-1.24)	.590
Mismatched	2.4 (1.51-3.82)	.000		1.7 (1.19-2.42)	.003

CIBMTR, Center for International Blood and Marrow Transplant Research; CMV, cytomegalovirus.