Fig. 2.

Serial MRI changes of case 2. A & B Brain scan (axial T2 and sagittal FLAIR sequences respectively) at the time of the diagnosis of MS. Note multiple pericallosal lesions consistent with Dawson’s fingers. C & D Brain scan (axial T2 and sagittal FLAIR sequences respectively) six years later when Alemtuzumab therapy was commenced. Note changes similar to A & B. E–G Images when MOG antibody test was found to be positive. E (brain axial FLAIR), F (sagittal FLAIR), and F (coronal FLAIR) shows multiple pericallosal lesions. H (sagittal T2 spine) shows multiple lesions at cervico-medullary junction, C2, C4, C6, and upper thoracic level