Table 3.
Statistical details for DMRs between LGG and GBM
| Chromosome | Start | End | Width | Strand | no.CpGsa | min_smoothed_fdrb | Stoufferc | HMFDRd | Fishere | Maxdifff | Meandiffg | Overlapping.genes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| chr13 | 78491982 | 78494462 | 2481 | * | 49 | 4.97E−154 | 2.40E−122 | 2.52E−10 | 3.81E−137 | 0.335893 | 0.086379 | OBI1-AS1, EDNRB |
| chr13 | 79168044 | 79168573 | 530 | * | 6 | 3.38E−45 | 8.34E−37 | 1.81E−09 | 4.87E−35 | 0.343167 | 0.220062 | OBI1-AS1 |
| chr13 | 79181440 | 79184529 | 3090 | * | 14 | 1.88E−28 | 4.46E−21 | 4.91E−08 | 9.10E−31 | 0.294686 | 0.02905 | OBI1-AS1 |
ano.CpGs: Number of constituent CpG sites of DMR
bmin_smoothed_fdr: Minimum FDR of the smoothed estimate
cStouffer: Stouffer summary transform of the individual CpG FDRs
dHMFDR: Harmonic mean of the individual CpG FDRs
eFisher: Fisher combined probability transform of the individual CpG FDRs
fmaxdiff: Maximum differential/coefficient within the DMR
gmeandiff: Mean differential/coefficient across the DMR