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. 2022 Mar 8;12(3):e060000. doi: 10.1136/bmjopen-2021-060000

Table 2.

Pulmonary Embolism Prevention after HiP and KneE Replacement inferiority margins with observed event rates for both aspirin comparison

Event rate (%) Rivaroxaban/aspirin comparison Warfarin/aspirin comparison
Absolute difference (%) Relative difference Absolute difference (%) Relative difference
2.5 0.935 1.374 0.902 1.361
3.0 1.023 1.341 0.984 1.328
3.5 1.102 1.315 1.060 1.303

*StatisicalAnalysisPlan, ThePEPPERTrial.atwww.PEPPERstudy.org