Table 3.
All SLE | Prevalent SLE | Incident SLE | |||||||
n | rs | Pvalue | n | rs | Pvalue | n | rs | Pvalue | |
Plasma ATX | 95 | −0.17 | 0.0998 | 69 | −0.17 | 0.1695 | 26 | −0.18 | 0.3717 |
Platelet activation | 39 | 22 | 17 | ||||||
PAC1+ | 0.09 | 0.5859 | −0.08 | 0.7141 | 0.46 | 0.0646 | |||
PAC1+ ATX+ | 0.02 | 0.9032 | −0.18 | 0.4273 | 0.41 | 0.1040 | |||
CD62P+ | 0.48 | 0.0021 | 0.43 | 0.0479 | 0.59 | 0.0127 | |||
CD62P+ ATX+ | 0.19 | 0.2492 | 0.03 | 0.8818 | 0.56 | 0.0207 | |||
PAC1+ CD62P+ | 0.27 | 0.0927 | 0.01 | 0.9790 | 0.65 | 0.0045 | |||
PAC1+ CD62P+ ATX+ | 0.12 | 0.4565 | −0.04 | 0.8600 | 0.43 | 0.0817 | |||
PEVs | 99 | 72 | 27 | ||||||
Total | 0.06 | 0.5377 | 0.01 | 0.9093 | 0.28 | 0.1574 | |||
PS+ | 0.05 | 0.6389 | 0.00 | 0.9842 | 0.25 | 0.2122 | |||
REVs | 99 | 72 | 27 | ||||||
Total | −0.07 | 0.4806 | −0.09 | 0.4623 | 0.04 | 0.8275 | |||
PS+ | −0.08 | 0.4274 | −0.12 | 0.3166 | 0.16 | 0.4325 |
Significant pvalues are in bold.
ATX, autotaxin; EV, extracellular vesicle; PEV, platelet EV; PS+, phosphatidylserine positive; REV, red blood cell EV; SLE, systemic lupus erythematosus.