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. 2022 Mar 8;9(1):e000605. doi: 10.1136/lupus-2021-000605

Table 3.

Spearman correlation between the platelet activation markers, EV levels and the SLEDAI score

All SLE Prevalent SLE Incident SLE
n rs Pvalue n rs Pvalue n rs Pvalue
Plasma ATX 95 −0.17 0.0998 69 −0.17 0.1695 26 −0.18 0.3717
Platelet activation 39 22 17
PAC1+ 0.09 0.5859 −0.08 0.7141 0.46 0.0646
PAC1+ ATX+ 0.02 0.9032 −0.18 0.4273 0.41 0.1040
CD62P+ 0.48 0.0021 0.43 0.0479 0.59 0.0127
CD62P+ ATX+ 0.19 0.2492 0.03 0.8818 0.56 0.0207
PAC1+ CD62P+ 0.27 0.0927 0.01 0.9790 0.65 0.0045
PAC1+ CD62P+ ATX+ 0.12 0.4565 −0.04 0.8600 0.43 0.0817
PEVs 99 72 27
Total 0.06 0.5377 0.01 0.9093 0.28 0.1574
PS+ 0.05 0.6389 0.00 0.9842 0.25 0.2122
REVs 99 72 27
Total −0.07 0.4806 −0.09 0.4623 0.04 0.8275
PS+ −0.08 0.4274 −0.12 0.3166 0.16 0.4325

Significant pvalues are in bold.

ATX, autotaxin; EV, extracellular vesicle; PEV, platelet EV; PS+, phosphatidylserine positive; REV, red blood cell EV; SLE, systemic lupus erythematosus.