Table 5.
Effects of DBA 3 and CUR in female BALB/c mice for 14 days in the acute toxicity study
| Groups | DA/TA | Mortality (%) | Latency to mortality (min) | Signs of toxicity |
|---|---|---|---|---|
| CN | 0/5 | 0 | – | None |
| DBA (3)300 | 0/5 | 0 | – | None |
| DBA (3)1000 | 0/5 | 0 | – | None |
| CUR300 | 0/5 | 0 | – | None |
| CUR1000 | 0/5 | 0 | – | None |
Note: Signs of toxicity assessed: general appearance; ataxia; vocal fremitus; irritability; body tone; tremor; salivation; tearing; palpable ptosis; seizures; and abnormal movements.
Abbreviations: CN, control (vehicle, n = 5); DBA (3)300, dose 300 mg/kg (n = 5); DBA (3)1000, dose 1,000 mg/kg (n = 5); CUR300, dose 300 mg/kg (n = 5); CUR1000, dose 1,000 mg/kg (n = 5); DA, dead animals; TA, total animals.