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IC50s, IC90s, and fold increases in resistance for various HIV-1 clones
| Virus | Mutation(s) | IC50 (μM) | IC90 (μM) |
|---|---|---|---|
| xxBRUpitt | 0.6 | 1.3 | |
| 181C/YEU | Y181C | 0.4 | 0.7 |
| HIV-1SUM9 | 0.4 | 0.9 | |
| HIV-1SUM8 | Q151M | 0.9 (2)a | 2.8 (2.8) |
| HIV-1SUM12 | F77L/F116Y/Q151M | 2.7 (6.4) | 6.8 (6.8) |
| HIV-1SUM13 | A62V/V75I/F77L/F116Y/Q151M | 3.3 (8) | 8.2 (8.2) |
| M184Vpitt | M184V | >10 (>20) | >10 (>10) |
Values in parentheses are fold resistance (fold increase in ICs relative to the mean IC50s and IC90s for wild-type HIV-1).
