Table 1.
Half-life of different molecules after intra-articular injection
| Molecule | Half-life (h) | Molecular Weight (Da) |
|---|---|---|
| Paracetamol(58) | 1.10 | 151 |
| Ibuprofen(59) | 2.20 | 206 |
| Naproxen(60) | 1.60 | 230 |
| Ketoprofen(60) | 1.90 | 254 |
| Diclofenac(58) | 5.20 | 296 |
| Cortisone(44) | 1.46 | 360 |
| Dexamethasone(43) | 3.60 | 392 |
| Methotrexate(61) | 2.90 | 454 |
| Hyaluronic acid(18) | 13.20 | 6,000 |
| IL-1Ra(62) | 23.04 | 65,400 |
| Bovine serum albumin(63) | 15.12 | 66,000 |