TABLE 3.

Treatment Effectiveness

	Intention to Treat			Per Protocol
	Imiquimod N=61	LLETZ N=62	P	Imiquimod N=47	LLETZ N=61	P
Successful treatment*	26 (43%)	58 (94%)	<0.01	28 (60%)	58 (95%)	<0.01

^*Defined as the absence of high-grade dysplasia at the first follow-up interval after treatment (20 wk for imiquimod and 26 wk for LLETZ treatment), assessed by diagnostic biopsies for the imiquimod group and cervical cytology followed by colposcopy with biopsies on indication for the LLETZ group.

LLETZ indicates large loop excision of the transformation zone.