TABLE 5.
Side-effects of Imiquimod Treatment, Reported First 8 Weeks*
| Side Effect, Overall | Side Effect, VAS ≥8 | |||
|---|---|---|---|---|
| N=42 | No. Patients (%) | Mean Duration (d) | No. Patients (%) | Mean Duration (d) |
| Headache | 39 (93) | 13.9 | 22 (52) | 3.3 |
| Fever | 29 (69) | 4.5 | 13 (31) | 2.4 |
| Fatigue | 36 (86) | 11.4 | 16 (38) | 6.4 |
| Myalgia | 34 (81) | 8.9 | 11 (26) | 4.5 |
| Vaginal discharge | 29 (69) | 10.4 | 6 (13) | 3.5 |
| Vaginal blood loss | 27 (64) | 6.0 | 5 (12) | 5.2 |
| Vulvar pruritus/pain | 34 (81) | 9.5 | 16 (38) | 3.1 |
| Vulvar redness | 18 (43) | 2.4 | 6 (14) | 4.7 |
*
Outcomes were available for 42 of 50 women (84%) who completed the first 8 weeks of the treatment protocol, but for only 14 women in the second 8 weeks. Therefore, only side effects reported in the first 8 weeks were analyzed and presented.