FIGURE 4.

Deletion of neutrophil extracellular traps (NETs) can alleviate IMQ induced psoriasis symptoms in mice. (A) The protein level of PAD4 in mice dorsal skin, tested by western blot. (B) Phenotypic presentation of sham‐ or IMQ‐treated PAD4 KO and WT mice, scale bar = 5 mm. (C) H&E staining of back skin sections of sham‐ or IMQ‐treated PAD4 KO and WT mice, scale bar = 200 μm. Clinical scores (D) or epidermal thickness (E) of mice dorsal skin. (F) Dorsal skin was infiltrated with TNF‐α, IL‐1β, IL‐17a, and CXCL15 evaluated by ELISA