Table 4.
Univariate and multivariate analysis of the independent variables associated with non-alcoholic steatohepatitis (NASH) in patients with obstructive sleep apnea (OSA) (n = 153).
| Independent variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Age (years) | 1.00 | (0.96–1.03) | 0.887 | |||
| Sex (female/male) | 1.82 | (0.93–3.56) | 0.081 | 2.89 | (1.32–6.35) | 0.008 |
| BMI (kg/m2) | 1.12 | (1.05–1.20) | <0.001 | 1.12 | (1.04–1.20) | 0.003 |
| Diabetes (no/yes) | 3.82 | (1.43–10.20) | 0.007 | 3.50 | (1.19–10.28) | 0.022 |
| AHI (mild/high) | 1.65 | (0.84–3.24) | 0.143 | |||
| ODI (low/high) | 1.24 | (0.52–2.97) | 0.631 | |||
| Tc90% (low/high) | 2.78 | (1.44–5.36) | 0.002 | 2.32 | (1.12–4.81) | 0.023 |
OSA, obstructive sleep apnea; OR, odds ratio; CI, confidence interval; BMI, body mass index; AHI, apnea-hypopnea index; ODI, oxygen desaturation index; Tc90%, percentage of sleep time with oxygen saturation <90%.