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. 2022 Mar 9;19(3):e1003943. doi: 10.1371/journal.pmed.1003943

Table 6. Effects of matrix, soy quality, and milk content in supplementary foods on SC (pmol/L) at end of the 3 months supplementation among 1,016 children with MAM1.

Main effects Effect of LNS versus CSB by soy quality Effects of SI versus DS by matrix
SI DS LNS CSB
Matrix
LNS 162 (3; 29) 0.02 39 (20; 57) <0.001 −8 (−26; 11) 0.42
CSB - - - -
Soy quality
SI −112 (−24; 2) 0.10 11 (−6; 30) 0.27 −35 (−53; −16) <0.001
DS - - - -
Milk content (% of protein)
50% 9 (−7; 25) 0.30
20% −2 (−18; 14) 0.84
0% - -

1Data shown as mean difference (95% CI) based on intention-to-treat population. Tobit regression adjusted for baseline measure of the outcome, WLZ, LAZ, MUAC, age, sex, month of admission, and site.

2Interaction between matrix and soy quality: p < 0.001.

CSB, corn–soy blend; DS, dehulled soy; LAZ, length-for-age z-score; LNS, lipid-based nutrient supplement; MAM, moderate acute malnutrition; MUAC, mid-upper arm circumference; SC, serum cobalamin; SI, soy isolate; WLZ, weight-for-length z-score.