Table 5. Predictors of in-hospital mortality using multivariable logistic regression with stepwise backward variable selection to minimize the AIC value.

Variable	Adjusted OR	95% CI	P value
Demographics & comorbidities
Age (per 10 years)	1.300	1.116–1.514	0.0008
Female sex	0.713	0.492–1.034	0.0741
Charlson Comorbidity Index (per point)	1.127	1.056–1.202	0.0003
History of diabetes mellitus	0.652	0.436–0.975	0.04
Year of admission (per year)	0.904	0.843–0.970	0.005
Admission diagnoses
Respiratory failure	2.525	1.661–3.836	<0.0001
Sepsis	2.106	1.294–3.429	0.0027
Severity of illness
APACHE score (per 10 points)	1.223	1.096–1.364	0.0003
Day 1 SOFA score (per point)	0.890	0.813–0.974	0.01
Admission Braden Skin Score (per point)	0.900	0.844–0.960	0.0013
Shock severity
SCAI shock stage (per stage)	1.243	1.024–1.508	0.03
Inodilators in first 24 hours	1.864	1.054–3.296	0.03
Procedures and therapies
Angiogram without PCI vs. no angiogram	0.726	0.473–1.112	0.14
PCI vs. no angiogram	0.424	0.267–0.673	0.0003
PCI vs. angiogram without PCI	0.583	0.348–0.980	0.04
pVAD or ECMO	6.021	1.621–22.365	0.0073
Dialysis	2.005	0.826–4.866	0.12
CRRT	3.272	1.001–10.698	0.05
Cardiac arrest
VF CA vs. no CA	3.036	1.795–5.135	<0.0001
Non-VF CA vs. no CA	6.878	4.112–11.505	<0.0001
VF CA vs. non-VF CA	2.266	1.246–4.121	0.007
IHCA	3.372	1.740–6.534	0.02
LVSWI (per 10 J/m2)	0.664	0.564–0.782	<0.0001

Data are displayed as adjusted odds ratio (OR) and 95% confidence interval (CI) values. The final model C-statistic value was 0.927 for discrimination of in-hospital mortality. Candidate variables which were not selected for the model included APACHE-IV predicted hospital mortality; race; invasive and noninvasive ventilator use; history of myocardial infarction, heart failure, chronic kidney disease, dialysis and stroke; peak VIS and NEE in first 24 hours; use of vasopressors in first 24 hours; IABP and PAC use; blood transfusion; CardShock score; LVEF; and admission diagnosis of heart failure or acute coronary syndrome.