Table 2.

Unadjusted Differences in Post-Covid Symptom Scores Among Vaccinated Compared to Unvaccinated Patients

Domain	Vaccinated		Non-vaccinated		Difference change vaccinated vs. non-vaccinated (95% CI)	p value
	Baseline Mean (SD)	Change	Baseline Mean (SD)	Change
Anosmia (N = 163)	2.44 (0.67)	− 0.58	2.40 (0.74)	− 0.33	− 0.26 (− 0.54 to 0.03)	0.08
Respiratory symptoms
Dyspnea (N = 286)	0.57 (0.50)	− 0.09	0.58 (0.50)	− 0.12	0.02 (− 0.19 to 0.23)	0.83
Cough (N = 231)	2.33 (0.81)	− 0.56	2.26 (0.85)	− 0.57	0.003 (− 0.39 to 0.39)	0.99
Phlegm (N = 146)	2.30 (0.85)	− 0.82	2.37 (0.85)	− 0.53	− 0.28 (− 0.76 to 0.20)	0.25
Wheezing (N = 101)	2.41 (0.78)	− 0.82	2.46 (0.69)	− 1.23	0.41 (− 0.27 to 1.09)	0.23
Depression symptoms (N = 288)	10.70 (5.02)	1.86	10.20 (4.05)	1.53	0.32 (− 0.88 to 1.53)	0.60
Anxiety symptoms (N = 212)	9.88 (4.08)	2.50	9.97 (5.03)	1.21	1.29 (− 0.24 to 2.82)	0.10
Covid PTSD symptoms (N = 127)	40.16 (12.16)	9.99	38.26 (11.64)	6.58	3.41 (− 1.82 to 8.63)	0.20
Non-Covid PTSD symptoms (N = 42)	34.00 (8.59)	14.38	44.38 (12.47)	12.07	2.32 (− 8.46 to 13.09)	0.66
Quality of life
Physical function (N = 218)	37.41 (4.65)	− 4.02	35.92 (4.76)	− 3.07	− 0.95 (− 2.96 to 1.05)	0.35
Anxiety (N = 244)	62.42 (5.41)	4.07	62.83 (6.84)	3.73	0.33 (− 1.98 to 2.65)	0.78
Depression (N = 171)	60.56 (5.05)	4.18	61.94 (5.49)	3.44	0.74 (− 1.81 to 3.29)	0.57
Fatigue (N = 261)	63.36 (6.06)	3.14	65.51 (6.39)	4.54	− 1.40 (− 3.98 to 1.18)	0.29
Social roles (N = 135)	58.78 (7.26)	3.49	56.39 (9.47)	5.81	− 2.32 (− 5.51 to 0.87)	0.15
Sleep (N = 171)	61.20 (4.60)	3.92	62.56 (5.59)	2.76	1.16 (− 1.10 to 3.41)	0.31
Pain (N = 232)	62.14 (5.59)	3.86	63.22 (5.58)	4.70	− 0.84 (− 3.19 to 1.52)	0.49

SD standard deviation, CI confidence interval