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. 2022 Mar 9;37(7):1748–1753. doi: 10.1007/s11606-022-07465-w

Table 3.

Adjusted Associations Between Vaccination and Post-Covid-19 Symptoms According to the Number of Doses

Domain Mean difference vaccinated vs. non-vaccinated (95% CI)
Primary analyses Secondary analyses
One or two doses One dose Two doses
Anosmia − 0.02 (− 0.35 to 0.31) − 0.17 (− 0.62 to 0.28) − 0.13 (− 0.42 to 0.15)
Respiratory symptoms
  Dyspnea 0.05 (− 0.15 to 0.25) 0.10 (− 0.20 to 0.39) − 0.06 (− 0.29 to 0.16)
  Cough − 0.17 (− 0.55 to 0.22) 0.22 (− 0.27 to 0.72) − 0.32 (− 0.73 to 0.08)
  Phlegm − 0.47 (− 0.87 to 0.10) − 0.28 (− 0.92to 0.36) − 0.27 (− 0.76 to 0.21)
  Wheezing − 0.16 (− 0.83 to 0.50) − 0.30 (− 1.17 to 0.56) − 0.28 (− 0.98 to 0.42)
Depression symptoms 0.02 (− 1.18 to 1.22) 0.39 (− 1.15 to1.95) 0.31 (− 0.95 to 1.56)
Anxiety symptoms 0.51 (− 0.93 to 0.04) 1.87 (− 0.01 to 3.76) 0.62 (− 0.71 to 1.95)
Covid PTSD symptoms 2.53 (− 3.06 to 8.12) 7.58 (− 0.21 to 15.37) 2.90 (− 2.13 to 7.93)
Non − Covid PTSD symptoms − 2.53 (− 12.11 to 7.04) − 11.62 (− 26.04 to 2.80) − 1.75 (− 11.85 to 8.35)
Quality of life
  Physical function − 1.16 (− 3.35 to 1.02) − 0.30 (− 2.95 to 2.36) − 0.87 (− 3.04 to 1.30)
  Anxiety − 0.29 (− 2.84 to 2.27) − 0.26 (− 3.24 to 2.72) − 0.69 (− 3.06 to 1.68)
  Depression − 1.12 (− 3.80 to 1.56) − 1.53 (− 5.09 to 2.04) 1.53 (− 1.22 to 4.28)
  Fatigue − 1.42 (− 4.15 to 1.32) − 1.15 (− 4.29 to 2.00) − 1.39 (− 3.93 to 1.15)
  Social roles − 0.17 (− 3.18 to 2.83) − 0.23 (− 3.67 to 4.13) − 1.99 (− 5.11 to 1.14)
  Sleep 1.51 (− 0.86 to 3.87) 1.00 (− 1.72 to 3.74) 1.95 (− 0.21 to 4.10)
  Pain − 0.02 (− 2.74 to 2.70) − 1.91 (− 4.74 to 0.92) − 0.40 (− 2.69 to 1.89)

CI confidence interval