Table 2:
Analgesics that the patients with lung cancer received for chronic postoperative pain after video-assisted thoracoscopic surgery between patients with and without AC within 3 months after surgery during the study period
| AC group (n = 68) | Non-AC group (n = 281) | P-value | |
|---|---|---|---|
| No medication | 8 (11.8) | 63 (22.4) | 0.051 |
| Acetaminophen | 20 (35.7) | 42 (20.0) | 0.014 |
| Anticonvulsantsa | 16 (23.5) | 20 (7.1) | 0.001 |
| Antidepressantsb | 6 (8.8) | 14 (5.0) | 0.222 |
| Lidocaine transdermal patch | 4 (5.9) | 12 (4.3) | 0.569 |
| Nonsteroidal anti-inflammatory drugs | 24 (35.3) | 82 (29.2) | 0.326 |
| Weak opioidsc | 56 (82.4) | 210 (74.7) | 0.186 |
| Strong opioidsd | 36 (52.9) | 66 (23.5) | <0.001 |
| Prolonged strong opioid use (≥3 months) | 13 (19.1) | 23 (8.2) | 0.008 |
The values are presented as the median (interquartile range) or n (%).
a
Gabapentin, pregabalin.
b
Serotonin-norepinephrine reuptake inhibitors, tricyclic antidepressants.
c
Tramadol, tramadol/acetaminophen combination.
d
Hydrocodone, hydromorphone, morphine, oxycodone, transdermal fentanyl patch.
AC: adjuvant chemotherapy.