Table 2.
Fold-Change in Leptin and Adiponectin for Every 10% Increase in Body Composition Parameter From Baseline to Week 96
| Leptin | Adiponectin | |||||
|---|---|---|---|---|---|---|
| Parameter | Adjusteda Fold Change at 96 Weeks | (95% CI) | P Value | Adjusteda Fold Change at 96 Weeks | (95% CI) | P Value |
| Trunk fat | 1.13 | (1.11–1.15) | <.001 | 0.95 | (.93–.96) | <.001 |
| Limb fat | 1.14 | (1.11–1.16) | <.001 | 0.94 | (.92–.96) | <.001 |
| SAT | 1.08 | (1.06–1.09) | <.001 | 0.97 | (.96–.99) | <.001 |
| VAT | 1.03 | (1.02–1.04) | <.001 | 0.98 | (.98–.99) | <.001 |
| BMIb | 1.05 | (1.05–1.06) | <.001 | 0.98 | (.97–.98) | <.001 |
Abbreviations: BMI, body mass index; CI, confidence interval; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue.
aAdjusted for sex, race/ethnicity, and baseline age, viral load, CD4 count, and BMI.
bFold-change per 1% increase in BMI; BMI model does not adjust for BMI as a covariate.