Table 2:

Clinical course after ECLS implantation, status at hospital discharge and at 30 days as predictors of medium-term survival

	n	Median (IQR) or frequency (%)	HR	P-value
Course of hospitalization
Duration of support (h)	79	109.8 (71.9–162.0)	1.00	0.46
VAD implantation	79	11 (13.9)	2.57	0.03
Heart transplantation	79	1 (1.3)	<0.001	1.00
Patients with adverse events	79	54 (68.4)	2.50	0.06
ECLS-related bleeding	79	6 (7.6)	0.42	0.40
Distal leg ischaemia	79	4 (5.1)	<0.001	1.00
Cerebral complication	79	24 (30.4)	2.38	0.02
RRT	78a	33 (42.3)	2.25	0.04
Sepsis	79	19 (24.1)	1.93	0.10
Bowel ischaemia	79	2 (2.5)	1.44	0.72
Duration of ventilation (days)	79	13.0 (8.0–22.0)	1.04	0.002
Tracheostomy	79	43 (54.4)	2.46	0.04
ICU stay (days)	79	20.0 (15.0–32.0)	1.02	0.05
Hospital stay (days)	79	24.0 (19.0–37.0)	1.01	0.41
Discharge
Home	79	9 (11.4)	0.35	0.30
To rehab	79	31 (39.2)	0.25	0.01
To other hospital	79	35 (44.3)	4.75	0.002
Died in-hospital after 30  days	79	4 (5.1)	na	na
Status at 30 days
Pulmonary status at 30 days
Not ventilated	79	50 (63.3)	0.27	<0.001
Intermittently ventilated	79	20 (25.3)	1.68	0.20
Fully ventilated	79	9 (11.4)	5.07	<0.001
Renal status at 30 days
No treatment	78a	11 (14.1)	0.52	0.37
Oral diuretics	78a	58 (74.4)	1.15	0.77
IV diuretics	78a	0	na	na
RRT	78a	9 (11.5)	1.37	0.56
Liver status at 30 days
Unremarkable	79	23 (29.1)	0.26	0.03
Elevated bilirubin/GOT/GPT	79	51 (64.6)	1.22	0.63
Complicationb	79	5 (6.3)	59.79	<0.001
Degree of dependence at 30 days
Rankin Scale ≤3	79	36 (45.6)	0.07	<0.001
Rankin Scale ≥3	79	43 (54.4)	15.20	<0.001

^aOne patient with chronic dialysis pre-ECLS was excluded.

^bIncludes any complication related to the hepatobiliary system, e.g. non-cardiogenic shock-related liver failure or secondary sclerosing cholangitis.

HR: hazard ratio; ICU: intensive care unit; IQR: interquartile range; na: not applicable; RRT: renal replacement therapy; VAD: ventricular assist device.