Table 4:
Univariable and multivariable analysis for identifying independent risk factors for recurrence in any sites during follow-up periods
| Univariable analysis |
Multivariable analysis |
|||||
|---|---|---|---|---|---|---|
| Variables | Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value |
| Age | ||||||
| >65 | 5.0 | 1.11–23.16 | 0.036 | 5.4 | 0.87–33.35 | 0.070 |
| Gender | ||||||
| Men | 5.8 | 1.63–20.49 | 0.007 | 3.9 | 0.86–17.24 | 0.078 |
| Smoking | ||||||
| Current/ex | 3.6 | 1.12–11.4 | 0.032 | |||
| PPY | 1.0 | 1.00–1.06 | 0.043 | |||
| CT diameter | ||||||
| Total diameter | 1.2 | 1.05–1.35 | 0.009 | |||
| ≥2.0 cm | 4.8 | 1.05–22.03 | 0.043 | |||
| Solid | 1.2 | 1.09–1.41 | 0.001 | |||
| ≥1.5 cm | 2.0 | 0.57–7.23 | 0.269 | |||
| CT ratio (%) | 1.1 | 1.00–1.13 | 0.045 | 6.9 | 0.72–65.63 | 0.095 |
| ≥85% | 9.6 | 1.23–74.42 | 0.031 | |||
| Diameter | ||||||
| Total | 1.2 | 1.08–1.44 | 0.003 | |||
| ≥2.0 cm | 5.4 | 1.19–24.77 | 0.029 | |||
| Invasive | 1.2 | 1.08–1.38 | 0.002 | |||
| ≥1.5 cm | 7.5 | 0.96–57.90 | 0.054 | |||
| Pathological features | ||||||
| Lymphatic invasion | 10.4 | 1.83–59.52 | 0.008 | |||
| Micropapillary pattern | ||||||
| Positive | 10.6 | 2.20–51.53 | 0.003 | |||
| STAS | 4.9 | 1.33–18.18 | 0.017 | 5.9 | 1.18–30.09 | 0.031 |
| Distance | 1.6 | 1.02–2.63 | 0.040 | |||
| Changes in stages | ||||||
| Up | 4.7 | 1.25–17.54 | 0.022 | |||
CI: confidence interval; CT: consolidative tumour; PPY: pack per year; STAS: spread through air spaces.