Figure 2.

Mean (+SEM) trials to criterion data for the attentional set-shifting task. A, Preoperative test session. B, Postoperative test session. MD lesion rats were significantly slower to learn the SD and the ED subtasks compared with MD sham controls (*p < 0.001). MD sham control rats, like MD lesion rats, needed more trials to learn the ED, as expected. However, the MD lesion rats required significantly fewer trials to criterion to learn REV3, the reversal occurring immediately after the ED, compared with the MD sham controls (*p < 0.001). Also see Extended Data Figure 2-1 showing boxplots of the mean trials to criterion for individual rats during the postoperative session of the attentional set-shifting task.