Figure 4.
Signatures of the intestinal BAs. Localization of sampling along the GI for BA signature determination in Sham group (A) and OAGB group (B). Intestinal BA signature in gall bladder (C), proximal biliary limb (D), distal biliary limb (E), proximal common limb (F), distal common limb (G); cecal content (H), and feces (I). J: intestinal free/conjugated BA ratio; K: intestinal primary/secondary BA ratio (C–K). Blue bar: sham group and green bar: OAGB group. Statistical analysis: linear trend and two-way ANOVA (A), two-way ANOVA (B), and one-way ANOVA (E–K). ***P < 0.001. BA, bile acid; GI, gastrointestinal; OAGB, one anastomosis gastric bypass.
