Figure 2.

Patient attrition.

Notes: ^a Moderate COPD exacerbations were defined as an outpatient or ER visit with a COPD exacerbation diagnosis code in the primary position and at least one dispensing/administration of a systemic corticosteroid or guideline-recommended antibiotic within 5 days following, or prior to, the visit. Severe COPD exacerbations were defined as an inpatient hospitalization with a diagnosis code for COPD exacerbation in the primary position. ^b Continuous eligibility was defined as continuous health plan enrollment with medical and pharmacy coverage. ^c FF/UMEC/VI was identified using National Drug Codes: 0173–0887-10, 0173–0887-14, and 0173–0887-61. ^d Initiation of single-inhaler FF/UMEC/VI within 30 days from the index date. ^e Initiation of single-inhaler FF/UMEC/VI between 31 and 180 days after the index date.

Abbreviations: COPD, chronic obstructive pulmonary disease; ER, emergency room; FF/UMEC/VI, fluticasone furoate, umeclidinium, and vilanterol.