Table 4.
Logistic Regression Analysis of Smoking and EI
| Characteristics | Univariable Analysis | Multivariable Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Smoking | 4.185 (2.179~8.04) | <0.001 | 3.052 (1.342~6.938) | 0.008 |
| BMI, kg/m2 | 3.448 (1.967~6.044) | <0.001 | 2.429 (1.192~4.949) | 0.015 |
| FEV1%pred | 2.694 (1.63~4.451) | <0.001 | 1.954 (1.014~3.765) | 0.045 |
| KCO (60%≤KCO<80%) | 4.22 (2.235~7.967) | <0.001 | 2.828 (1.386~5.769) | 0.004 |
| KCO (<60%) | 18.739 (8.459~41.513) | <0.001 | 10.975 (4.716~25.544) | <0.001 |
| PaCO2 | 2.332 (1.151~4.725) | 0.019 | ||
| Comorbidities | 0.88 (0.538~1.44) | 0.611 | ||
| CAT | 0.967 (0.596~1.572) | 0.894 | ||
| Exacerbations/year | 1.181 (0.713~1.957) | 0.518 | ||
| mMRC | 1.257 (0.77~2.053) | 0.361 | ||
| Age | 0.978 (0.601~1.591) | 0.927 | ||
| PaO2 | 1.116 (0.574~2.17) | 0.747 | ||
Notes: After adjusting age (>65 years), FEV1%pred (<50%), BMI (<21), and DLCO/VA (<80%), the factor of smoking was related to emphysema formation EI (≥20%).