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. 1999 Feb;43(2):307–313. doi: 10.1128/aac.43.2.307

TABLE 4.

Kinetic parameters of SFO-1 and FEC-1 for β-lactam antibiotics

Substrate	SFO-1			FEC-1
Substrate	K_m (μM)	Relative V_max^a	Relative V_max/K_m^a	K_m (μM)	Relative V_max^a	Relative V_max/K_m^a
Cephaloridine	110	100	100	152	100	100
Cephalothin	60	234	428	134	198	225
Cefamandole	171	241	154	122	125	156
Cefotiam	27	50	203	38	43	170
Cefoperazone	6.6	15	246	2.8	2.6	139
Cefpiramide	26	71	297	33	36	167
Cefuroxime	13	23	195	27	32	179
Ceftizoxime	217	12	5.8	821	12	2.3
Cefotaxime	2.2	16	790	61	23	59
Cefmenoxime	21	20	108	84	61	110
Ceftriaxone	19	15	84	27	14	80
Ceftazidime	785	0.47	0.065	393	0.13	0.05
Ampicillin	40	19	51	30	17	89

^a

Values relative to that for hydrolysis of cephaloridine, which was set equal to 100.